Compressive Stimulation Enhances Ovarian Cancer Proliferation, Invasion, Chemoresistance, and Mechanotransduction via CDC42 in a 3D Bioreactor

This report investigates the role of compressive stress on ovarian cancer in a 3D custom built bioreactor. Cells within the ovarian tumor microenvironment experience a range of compressive stimuli that contribute to mechanotransduction. As the ovarian tumor expands, cells are exposed to chronic load...

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Detalles Bibliográficos
Autores principales: Novak, Caymen M., Horst, Eric N., Lin, Emily, Mehta, Geeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352213/
https://www.ncbi.nlm.nih.gov/pubmed/32532057
http://dx.doi.org/10.3390/cancers12061521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352213/
https://www.ncbi.nlm.nih.gov/pubmed/32532057
http://dx.doi.org/10.3390/cancers12061521

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