A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells

There is currently no effective long-term treatment for ovarian cancer (OC) resistant to poly-chemotherapy regimens based on platinum drugs. Preclinical and clinical studies have demonstrated a strong association between development of Pt-drug resistance and increased thymidylate synthase (hTS) expr...

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Detalles Bibliográficos
Autores principales: Marverti, Gaetano, Gozzi, Gaia, Maretti, Eleonora, Lauriola, Angela, Severi, Leda, Sacchetti, Francesca, Losi, Lorena, Pacifico, Salvatore, Ferrari, Stefania, Ponterini, Glauco, Leo, Eliana, Costi, Maria Paola, D’Arca, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352236/
https://www.ncbi.nlm.nih.gov/pubmed/32585842
http://dx.doi.org/10.3390/ijms21124452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352236/
https://www.ncbi.nlm.nih.gov/pubmed/32585842
http://dx.doi.org/10.3390/ijms21124452

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