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ABCA1/ApoE/HDL Signaling Pathway Facilitates Myelination and Oligodendrogenesis after Stroke

ATP-binding cassette transporter A1 (ABCA1) plays an important role in the regulation of apolipoprotein E (ApoE) and the biogenesis of high-density lipoprotein (HDL) cholesterol in the mammalian brain. Cholesterol is a major source for myelination. Here, we investigate whether ABCA1/ApoE/HDL contrib...

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Detalles Bibliográficos
Autores principales: Li, Li, Li, Rongwen, Zacharek, Alex, Wang, Fengjie, Landschoot-Ward, Julie, Chopp, Michael, Chen, Jieli, Cui, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352241/
https://www.ncbi.nlm.nih.gov/pubmed/32575457
http://dx.doi.org/10.3390/ijms21124369