Vav1 is Essential for HIF-1α Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells

The vascular response to hypoxia and ischemia is essential for maintaining homeostasis during stressful conditions and is particularly critical for vital organs such as the heart. Hypoxia-inducible factor-1 (HIF-1) is a central regulator of the response to hypoxia by activating transcription of nume...

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Detalles Bibliográficos
Autores principales: Hong, Jaewoo, Min, Yongfen, Wuest, Todd, Lin, P. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352305/
https://www.ncbi.nlm.nih.gov/pubmed/32471123
http://dx.doi.org/10.3390/cancers12061374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352305/
https://www.ncbi.nlm.nih.gov/pubmed/32471123
http://dx.doi.org/10.3390/cancers12061374

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