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Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism

Fifteen to 20% of pregnant women may exceed the recommended intake of folic acid (FA) by more than four-fold. This excess could compromise neurocognitive and motor development in offspring. Here, we explored the impact of an FA-supplemented diet (5× FASD, containing five-fold higher FA than recommen...

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Detalles Bibliográficos
Autores principales: Cosín-Tomás, Marta, Luan, Yan, Leclerc, Daniel, Malysheva, Olga V., Lauzon, Nidia, Bahous, Renata H., Christensen, Karen E., Caudill, Marie A., Rozen, Rima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352339/
https://www.ncbi.nlm.nih.gov/pubmed/32521649
http://dx.doi.org/10.3390/nu12061716