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Neuronal Repressor REST Controls Ewing Sarcoma Growth and Metastasis by Affecting Vascular Pericyte Coverage and Vessel Perfusion

Survival rates for Ewing sarcoma (ES) patients with metastatic disease have not improved in over 20 years. Tumor growth and metastasis are dependent on tumor vasculature expansion; therefore, identifying the regulators that control this process in ES may provide new therapeutic opportunities. ES exp...

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Detalles Bibliográficos
Autores principales: Zhou, Zhichao, Yang, Yuanzheng, Wang, Fei, Kleinerman, Eugenie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352345/
https://www.ncbi.nlm.nih.gov/pubmed/32486064
http://dx.doi.org/10.3390/cancers12061405