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Inhibition of ATM Increases the Radiosensitivity of Uveal Melanoma Cells to Photons and Protons

Treatment of uveal melanoma (UM) is generally successful, with local primary tumour control being at 90–95%. Localized radiotherapy in the form of plaque brachytherapy or proton beam radiotherapy is the most common treatment modality in the UK. However, the basic mechanisms of radiation response, DN...

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Detalles Bibliográficos
Autores principales: Hussain, Rumana N., Coupland, Sarah E., Khzouz, Jakub, Kalirai, Helen, Parsons, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352388/
https://www.ncbi.nlm.nih.gov/pubmed/32481544
http://dx.doi.org/10.3390/cancers12061388