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Negative Modulation of TRPM8 Channel Function by Protein Kinase C in Trigeminal Cold Thermoreceptor Neurons

TRPM8 is the main molecular entity responsible for cold sensing. This polymodal ion channel is activated by cold, cooling compounds such as menthol, voltage, and rises in osmolality. In corneal cold thermoreceptor neurons (CTNs), TRPM8 expression determines not only their sensitivity to cold, but al...

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Detalles Bibliográficos
Autores principales: Rivera, Bastián, Campos, Matías, Orio, Patricio, Madrid, Rodolfo, Pertusa, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352406/
https://www.ncbi.nlm.nih.gov/pubmed/32580281
http://dx.doi.org/10.3390/ijms21124420