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Targeted Osmotic Lysis of Highly Invasive Breast Carcinomas Using Pulsed Magnetic Field Stimulation of Voltage-Gated Sodium Channels and Pharmacological Blockade of Sodium Pumps

Concurrent activation of voltage-gated sodium channels (VGSCs) and blockade of Na(+) pumps causes a targeted osmotic lysis (TOL) of carcinomas that over-express the VGSCs. Unfortunately, electrical current bypasses tumors or tumor sections because of the variable resistance of the extracellular micr...

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Detalles Bibliográficos
Autores principales: Paul, Dennis, Maggi, Paul, Piero, Fabio Del, Scahill, Steven D., Sherman, Kelly Jean, Edenfield, Samantha, Gould, Harry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352419/
https://www.ncbi.nlm.nih.gov/pubmed/32486340
http://dx.doi.org/10.3390/cancers12061420