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Targeted Osmotic Lysis of Highly Invasive Breast Carcinomas Using Pulsed Magnetic Field Stimulation of Voltage-Gated Sodium Channels and Pharmacological Blockade of Sodium Pumps
Concurrent activation of voltage-gated sodium channels (VGSCs) and blockade of Na(+) pumps causes a targeted osmotic lysis (TOL) of carcinomas that over-express the VGSCs. Unfortunately, electrical current bypasses tumors or tumor sections because of the variable resistance of the extracellular micr...
Autores principales: | Paul, Dennis, Maggi, Paul, Piero, Fabio Del, Scahill, Steven D., Sherman, Kelly Jean, Edenfield, Samantha, Gould, Harry J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352419/ https://www.ncbi.nlm.nih.gov/pubmed/32486340 http://dx.doi.org/10.3390/cancers12061420 |
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