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Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma

Background: Predictive biomarkers of response to chemotherapy plus antiangiogenic for metastatic colorectal cancer (mCRC) are lacking. The objective of this study was to test the prognostic role of splenomegaly on baseline CT scan. Methods: This study is a sub-study of PRODIGE-9 study, which include...

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Detalles Bibliográficos
Autores principales: Niogret, Julie, Limagne, Emeric, Thibaudin, Marion, Blanc, Julie, Bertaut, Aurelie, Le Malicot, Karine, Rinaldi, Yves, Caroli-Bosc, François-Xavier, Audemar, Franck, Nguyen, Suzanne, Sarda, Corinne, Lombard-Bohas, Catherine, Locher, Christophe, Carreiro, Miguel, Legoux, Jean-Louis, Etienne, Pierre-Luc, Baconnier, Mathieu, Porneuf, Marc, Aparicio, Thomas, Ghiringhelli, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352427/
https://www.ncbi.nlm.nih.gov/pubmed/32486421
http://dx.doi.org/10.3390/cancers12061429