Optimization of a WGA-Free Molecular Tagging-Based NGS Protocol for CTCs Mutational Profiling

Molecular characterization of Circulating Tumor Cells (CTCs) is still challenging, despite attempts to minimize the drawbacks of Whole Genome Amplification (WGA). In this paper, we propose a Next-Generation Sequencing (NGS) optimized protocol based on molecular tagging technology, in order to detect...

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Detalles Bibliográficos
Autores principales: De Luca, Giuseppa, Cardinali, Barbara, Del Mastro, Lucia, Lastraioli, Sonia, Carli, Franca, Ferrarini, Manlio, Calin, George A., Garuti, Anna, Mazzitelli, Carlotta, Zupo, Simona, Dono, Mariella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352435/
https://www.ncbi.nlm.nih.gov/pubmed/32575430
http://dx.doi.org/10.3390/ijms21124364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352435/
https://www.ncbi.nlm.nih.gov/pubmed/32575430
http://dx.doi.org/10.3390/ijms21124364

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