Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a hematopoietic stem-cell-derived leukemia with often successive derived driver mutations. Late onset acquisition of internal tandem duplication in FLT3 (FLT3-ITD) at a high variant allele frequency often contributes to full transformation to a highly proliferative, r...

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Detalles Bibliográficos
Autores principales: Brinton, Lindsey T., Sher, Steven, Williams, Katie, Canfield, Daniel, Orwick, Shelley, Wasmuth, Ronni, Cempre, Casey, Skinner, Jordan, Lehman, Amy, Blachly, James S., Byrd, John C., Lapalombella, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352446/
https://www.ncbi.nlm.nih.gov/pubmed/32545904
http://dx.doi.org/10.3390/cancers12061574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352446/
https://www.ncbi.nlm.nih.gov/pubmed/32545904
http://dx.doi.org/10.3390/cancers12061574

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