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Ubiquitylation-Mediated Fine-Tuning of DNA Double-Strand Break Repair

The proper function of DNA repair is indispensable for eukaryotic cells since accumulation of DNA damages leads to genome instability and is a major cause of oncogenesis. Ubiquitylation and deubiquitylation play a pivotal role in the precise regulation of DNA repair pathways by coordinating the recr...

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Detalles Bibliográficos
Autores principales: Borsos, Barbara N., Majoros, Hajnalka, Pankotai, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352447/
https://www.ncbi.nlm.nih.gov/pubmed/32570875
http://dx.doi.org/10.3390/cancers12061617