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Development of a VLP-Based Vaccine Displaying an xCT Extracellular Domain for the Treatment of Metastatic Breast Cancer

Metastatic breast cancer (MBC) is the leading cause of cancer death in women due to recurrence and resistance to conventional therapies. Thus, MBC represents an important unmet clinical need for new treatments. In this paper we generated a virus-like particle (VLP)-based vaccine (AX09) to inhibit de...

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Detalles Bibliográficos
Autores principales: Rolih, Valeria, Caldeira, Jerri, Bolli, Elisabetta, Salameh, Ahmad, Conti, Laura, Barutello, Giuseppina, Riccardo, Federica, Magri, Jolanda, Lamolinara, Alessia, Parra, Karla, Valenzuela, Paloma, Francia, Giulio, Iezzi, Manuela, Pericle, Federica, Cavallo, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352461/
https://www.ncbi.nlm.nih.gov/pubmed/32521631
http://dx.doi.org/10.3390/cancers12061492