Cargando…

Suppression of Nonsense Mutations by New Emerging Technologies

Nonsense mutations often result from single nucleotide substitutions that change a sense codon (coding for an amino acid) to a nonsense or premature termination codon (PTC) within the coding region of a gene. The impact of nonsense mutations is two-fold: (1) the PTC-containing mRNA is degraded by a...

Descripción completa

Detalles Bibliográficos
Autores principales: Morais, Pedro, Adachi, Hironori, Yu, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352488/
https://www.ncbi.nlm.nih.gov/pubmed/32575694
http://dx.doi.org/10.3390/ijms21124394