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Suppression of Nonsense Mutations by New Emerging Technologies
Nonsense mutations often result from single nucleotide substitutions that change a sense codon (coding for an amino acid) to a nonsense or premature termination codon (PTC) within the coding region of a gene. The impact of nonsense mutations is two-fold: (1) the PTC-containing mRNA is degraded by a...
Autores principales: | Morais, Pedro, Adachi, Hironori, Yu, Yi-Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352488/ https://www.ncbi.nlm.nih.gov/pubmed/32575694 http://dx.doi.org/10.3390/ijms21124394 |
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