Rationally Designed Antibodies as Research Tools to Study the Structure–Toxicity Relationship of Amyloid-β Oligomers

Alzheimer’s disease is associated with the aggregation of the amyloid-β peptide (Aβ), resulting in the deposition of amyloid plaques in brain tissue. Recent scrutiny of the mechanisms by which Aβ aggregates induce neuronal dysfunction has highlighted the importance of the Aβ oligomers of this protei...

Descripción completa

Detalles Bibliográficos
Autores principales: Limbocker, Ryan, Mannini, Benedetta, Cataldi, Rodrigo, Chhangur, Shianne, Wright, Aidan K., Kreiser, Ryan P., Albright, J. Alex, Chia, Sean, Habchi, Johnny, Sormanni, Pietro, Kumita, Janet R., Ruggeri, Francesco S., Dobson, Christopher M., Chiti, Fabrizio, Aprile, Francesco A., Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352524/
https://www.ncbi.nlm.nih.gov/pubmed/32630615
http://dx.doi.org/10.3390/ijms21124542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352524/
https://www.ncbi.nlm.nih.gov/pubmed/32630615
http://dx.doi.org/10.3390/ijms21124542

Ejemplares similares