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Sialic Acid-Siglec Axis as Molecular Checkpoints Targeting of Immune System: Smart Players in Pathology and Conventional Therapy

The sialic acid-based molecular mimicry in pathogens and malignant cells is a regulatory mechanism that leads to cross-reactivity with host antigens resulting in suppression and tolerance in the immune system. The interplay between sialoglycans and immunoregulatory Siglec receptors promotes foreign...

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Detalles Bibliográficos
Autores principales: Wielgat, Przemyslaw, Rogowski, Karol, Niemirowicz-Laskowska, Katarzyna, Car, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352527/
https://www.ncbi.nlm.nih.gov/pubmed/32575400
http://dx.doi.org/10.3390/ijms21124361