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Targeting the CBP/β-Catenin Interaction to Suppress Activation of Cancer-Promoting Pancreatic Stellate Cells

Background: Although cyclic AMP-response element binding protein-binding protein (CBP)/β-catenin signaling is known to promote proliferation and fibrosis in various organ systems, its role in the activation of pancreatic stellate cells (PSCs), the key effector cells of desmoplasia in pancreatic canc...

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Detalles Bibliográficos
Autores principales: Che, Mingtian, Kweon, Soo-Mi, Teo, Jia-Ling, Yuan, Yate-Ching, Melstrom, Laleh G., Waldron, Richard T., Lugea, Aurelia, Urrutia, Raul A., Pandol, Stephen J., Lai, Keane K. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352534/
https://www.ncbi.nlm.nih.gov/pubmed/32516943
http://dx.doi.org/10.3390/cancers12061476