RAC1B Induces SMAD7 via USP26 to Suppress TGFβ1-Dependent Cell Migration in Mesenchymal-Subtype Carcinoma Cells

The small GTPase RAC1B has been shown to act as a powerful inhibitor of the transforming growth factor (TGF)β type I receptor ALK5 and TGFβ1/ALK5-induced epithelial–mesenchymal transition and cell motility. However, the precise mechanism has remained elusive. RNAi-mediated knockdown of RAC1B in the...

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Detalles Bibliográficos
Autores principales: Ungefroren, Hendrik, Kumarasinghe, Anuradha, Musfeldt, Melina, Fiedler, Christian, Lehnert, Hendrik, Marquardt, Jens-Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352540/
https://www.ncbi.nlm.nih.gov/pubmed/32545415
http://dx.doi.org/10.3390/cancers12061545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352540/
https://www.ncbi.nlm.nih.gov/pubmed/32545415
http://dx.doi.org/10.3390/cancers12061545

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