1,25(OH)(2)D(3) Alleviates Aβ(25-35)-Induced Tau Hyperphosphorylation, Excessive Reactive Oxygen Species, and Apoptosis Through Interplay with Glial Cell Line-Derived Neurotrophic Factor Signaling in SH-SY5Y Cells

Amyloid beta (Aβ) accumulation in the brain is one of the major pathological features of Alzheimer’s disease. The active form of vitamin D (1,25(OH)(2)D(3)), which acts via its nuclear hormone receptor, vitamin D receptor (VDR), has been implicated in the treatment of Aβ pathology, and is thus consi...

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Detalles Bibliográficos
Autores principales: Lin, Ching-I, Chang, Yi-Chen, Kao, Ning-Jo, Lee, Wei-Ju, Cross, Tzu-Wen, Lin, Shyh-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352552/
https://www.ncbi.nlm.nih.gov/pubmed/32545801
http://dx.doi.org/10.3390/ijms21124215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352552/
https://www.ncbi.nlm.nih.gov/pubmed/32545801
http://dx.doi.org/10.3390/ijms21124215

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