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Maackiain Ameliorates 6-Hydroxydopamine and SNCA Pathologies by Modulating the PINK1/Parkin Pathway in Models of Parkinson’s Disease in Caenorhabditis elegans and the SH-SY5Y Cell Line

The movement disorder Parkinson’s disease (PD) is the second most frequently diagnosed neurodegenerative disease, and is associated with aging, the environment, and genetic factors. The intracellular aggregation of α-synuclein and the loss of dopaminergic neurons in the substantia nigra pars compact...

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Detalles Bibliográficos
Autores principales: Tsai, Rong-Tzong, Tsai, Chia-Wen, Liu, Shih-Ping, Gao, Jia-Xin, Kuo, Yun-Hua, Chao, Pei-Min, Hung, Huey-Shan, Shyu, Woei-Cherng, Lin, Shinn-Zong, Fu, Ru-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352553/
https://www.ncbi.nlm.nih.gov/pubmed/32585871
http://dx.doi.org/10.3390/ijms21124455