A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation

Evidence suggests that the growth and therapeutic resistance of glioblastoma (GBM) may be enabled by a population of glioma stem cells (GSCs) that are regulated by typical stem cell pathways, including the WNT/β-catenin signaling pathway. We wanted to explore the effect of treating GSCs with a small...

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Detalles Bibliográficos
Autores principales: Kierulf-Vieira, Kirsten Strømme, Sandberg, Cecilie Jonsgar, Waaler, Jo, Lund, Kaja, Skaga, Erlend, Saberniak, Birthe Mikkelsen, Panagopoulos, Ioannis, Brandal, Petter, Krauss, Stefan, Langmoen, Iver Arne, Vik-Mo, Einar Osland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352564/
https://www.ncbi.nlm.nih.gov/pubmed/32575464
http://dx.doi.org/10.3390/cancers12061630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352564/
https://www.ncbi.nlm.nih.gov/pubmed/32575464
http://dx.doi.org/10.3390/cancers12061630

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