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Overcoming Platinum and PARP-Inhibitor Resistance in Ovarian Cancer

Platinum chemotherapy remains the cornerstone of treatment for epithelial ovarian cancer (OC) and Poly (ADP-ribose) polymerase inhibitors (PARPi) now have an established role as maintenance therapy. The mechanisms of action of these agents is, in many ways, complementary, and crucially reliant on th...

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Detalles Bibliográficos
Autores principales: McMullen, Michelle, Karakasis, Katherine, Madariaga, Ainhoa, Oza, Amit M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352566/
https://www.ncbi.nlm.nih.gov/pubmed/32560564
http://dx.doi.org/10.3390/cancers12061607