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New Anti-Cancer Strategy to Suppress Colorectal Cancer Growth Through Inhibition of ATG4B and Lysosome Function

Autophagy inhibition has been proposed to be a potential therapeutic strategy for cancer, however, few autophagy inhibitors have been developed. Recent studies have indicated that lysosome and autophagy related 4B cysteine peptidase (ATG4B) are two promising targets in autophagy for cancer therapy....

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Detalles Bibliográficos
Autores principales: Fu, Yuanyuan, Gu, Qianqian, Luo, Li, Xu, Jiecheng, Luo, Yuping, Xia, Fan, Han, Fanghai, Hong, Liang, Yin, Xiao-Ming, Huang, Zhiying, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352571/
https://www.ncbi.nlm.nih.gov/pubmed/32532053
http://dx.doi.org/10.3390/cancers12061523