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Cabozantinib Inhibits Photodynamic Therapy-Induced Auto- and Paracrine MET Signaling in Heterotypic Pancreatic Microtumors

Extensive desmoplasia is a hallmark of pancreatic ductal adenocarcinoma (PDAC), which frequently associates with treatment resistance. Recent findings indicate that a combination of photodynamic therapy and the multi-kinase inhibitor cabozantinib achieved local tumor control and a significant decrea...

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Detalles Bibliográficos
Autores principales: Broekgaarden, Mans, Alkhateeb, Ahmed, Bano, Shazia, Bulin, Anne-Laure, Obaid, Girgis, Rizvi, Imran, Hasan, Tayyaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352584/
https://www.ncbi.nlm.nih.gov/pubmed/32485915
http://dx.doi.org/10.3390/cancers12061401