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Use of a Luciferase-Expressing Orthotopic Rat Brain Tumor Model to Optimize a Targeted Irradiation Strategy for Efficacy Testing with Temozolomide

Glioblastoma multiforme (GBM) is a common and aggressive malignant brain cancer with a mean survival time of approximately 15 months after initial diagnosis. Currently, the standard-of-care (SOC) treatment for this disease consists of radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ...

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Detalles Bibliográficos
Autores principales: Mowday, Alexandra M., Lieuwes, Natasja G., Biemans, Rianne, Marcus, Damiënne, Rezaeifar, Behzad, Reniers, Brigitte, Verhaegen, Frank, Theys, Jan, Dubois, Ludwig J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352586/
https://www.ncbi.nlm.nih.gov/pubmed/32549357
http://dx.doi.org/10.3390/cancers12061585