Cargando…

Use of a Luciferase-Expressing Orthotopic Rat Brain Tumor Model to Optimize a Targeted Irradiation Strategy for Efficacy Testing with Temozolomide

Glioblastoma multiforme (GBM) is a common and aggressive malignant brain cancer with a mean survival time of approximately 15 months after initial diagnosis. Currently, the standard-of-care (SOC) treatment for this disease consists of radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mowday, Alexandra M., Lieuwes, Natasja G., Biemans, Rianne, Marcus, Damiënne, Rezaeifar, Behzad, Reniers, Brigitte, Verhaegen, Frank, Theys, Jan, Dubois, Ludwig J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352586/ https://www.ncbi.nlm.nih.gov/pubmed/32549357 http://dx.doi.org/10.3390/cancers12061585

Ejemplares similares

Evofosfamide sensitizes esophageal carcinomas to radiation without increasing normal tissue toxicity
por: Spiegelberg, Linda, et al.
Publicado: (2019)

Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy
por: Olivo Pimentel, Veronica, et al.
Publicado: (2021)

Inter-observer variability of organ contouring for preclinical studies with cone beam Computed Tomography imaging
por: Lappas, Georgios, et al.
Publicado: (2022)

‘On the Spot’ Digital Pathology of Breast Cancer Based on Single-Cell Mass Spectrometry Imaging
por: Cuypers, Eva, et al.
Publicado: (2022)

E. coli nitroreductase NfsA is a reporter gene for non-invasive PET imaging in cancer gene therapy applications
por: Mowday, Alexandra Marie, et al.
Publicado: (2020)

Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1α Stabilization and Expression of Its Downstream Targets
por: van Gisbergen, Marike W., et al.
Publicado: (2020)

In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity
por: Panth, Kranthi Marella, et al.
Publicado: (2016)

NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma
por: Yahyanejad, Sanaz, et al.
Publicado: (2016)

Selectively Targeting Tumor Hypoxia With the Hypoxia-Activated Prodrug CP-506
por: van der Wiel, Alexander M.A., et al.
Publicado: (2021)

Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure
por: Konings, Gonda FJ, et al.
Publicado: (2018)

The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses
por: Rekers, Nicolle H., et al.
Publicado: (2018)

The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy
por: van Kuijk, Simon J. A., et al.
Publicado: (2016)

Human fibronectin extra domain B as a biomarker for targeted therapy in cancer
por: Lieverse, Relinde I. Y., et al.
Publicado: (2020)

Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress
por: Mowday, Alexandra M., et al.
Publicado: (2016)

Retracted: Luciferase-transfected colon adenocarcinoma cell line (DLD-1) for use in Orthotopic Xenotransplantation studies
por: Siddique, Muhammad Rashid, et al.
Publicado: (2012)

Retraction: Luciferase-transfected colon adenocarcinoma cell line (DLD-1) for use in Orthotopic Xenotransplantation studies
por: Siddique, Muhammad Rashid, et al.
Publicado: (2012)

Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer
por: Baklaushev, V. P., et al.
Publicado: (2017)

Combining radiotherapy with immunotherapy: the past, the present and the future
por: Van Limbergen, Evert J, et al.
Publicado: (2017)

Cannabidiol inhibits RAD51 and sensitizes glioblastoma to temozolomide in multiple orthotopic tumor models
por: Soroceanu, Liliana, et al.
Publicado: (2022)

Hypoxia PET Imaging with [18F]-HX4—A Promising Next-Generation Tracer
por: Sanduleanu, Sebastian, et al.
Publicado: (2020)

Deep Learning Based Automated Orthotopic Lung Tumor Segmentation in Whole-Body Mouse CT-Scans
por: van de Worp, Wouter R. P. H., et al.
Publicado: (2021)

Treating colorectal peritoneal metastases with an injectable cytostatic loaded supramolecular hydrogel in a rodent animal model
por: Wintjens, Anne G. W. E., et al.
Publicado: (2023)

A novel orthotopic mouse model replicates human lung cancer cachexia
por: van de Worp, Wouter R.P.H., et al.
Publicado: (2023)

Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents
por: Turk, Amy N., et al.
Publicado: (2011)

Charged Particle and Conventional Radiotherapy: Current Implications as Partner for Immunotherapy
por: Marcus, Damiënne, et al.
Publicado: (2021)

Mifepristone Overcomes Tumor Resistance to Temozolomide Associated with DNA Damage Repair and Apoptosis in an Orthotopic Model of Glioblastoma
por: Llaguno-Munive, Monserrat, et al.
Publicado: (2018)

Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models
por: Gherardini, Lisa, et al.
Publicado: (2023)

Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines
por: Schatz, Julia, et al.
Publicado: (2022)

Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma
por: Gholamin, Sharareh, et al.
Publicado: (2019)

Temozolomide is additive with cytotoxic effect of irradiation in canine glioma cell lines
por: Tresch, Nina Simona, et al.
Publicado: (2021)

Mutational optimization of the coelenterazine-dependent luciferase from Renilla
por: Woo, Jongchan, et al.
Publicado: (2008)

Localization of the Catalytic Domain of Copepod Luciferases: Analysis of Truncated Mutants of the Metridia longa Luciferase
por: Markova, Svetlana V., et al.
Publicado: (2023)

[(18)F]VM4-037 MicroPET Imaging and Biodistribution of Two In Vivo CAIX-Expressing Tumor Models
por: Peeters, Sarah G. J. A., et al.
Publicado: (2015)

Substrate Cooperativity in Marine Luciferases
por: Tzertzinis, George, et al.
Publicado: (2012)

Luciferase‐free Luciferin Electrochemiluminescence
por: Belotti, Mattia, et al.
Publicado: (2022)

Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Igarashi, Kentaro, et al.
Publicado: (2017)

Temozolomide and Pazopanib Combined with FOLFOX Regressed a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model
por: Zhu, Guangwei, et al.
Publicado: (2020)

Synthetic versions of firefly luciferase and Renilla luciferase reporter genes that resist transgene silencing in sugarcane
por: Chou, Ting-Chun, et al.
Publicado: (2014)

Triple combination of lomustine, temozolomide and irradiation reduces canine glioma cell survival in vitro
por: Fuchs, Daniel, et al.
Publicado: (2023)

Approaches to engineer stability of beetle luciferases
por: Koksharov, Mikhail I., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_l02jn6v92age6fhiae4afck9mq