The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets

Background: Intercellular communication mediated by cationic fluxes through the Connexin family of gap junctions regulates glucose-stimulated insulin secretion and beta cell defense against inflammatory stress. Rotigaptide (RG, ZP123) is a peptide analog that increases intercellular conductance in c...

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Detalles Bibliográficos
Autores principales: Ghiasi, Seyed Mojtaba, Hansen, Jakob Bondo, Christensen, Dan Ploug, Tyrberg, Björn, Mandrup-Poulsen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352593/
https://www.ncbi.nlm.nih.gov/pubmed/32560352
http://dx.doi.org/10.3390/ijms21124311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352593/
https://www.ncbi.nlm.nih.gov/pubmed/32560352
http://dx.doi.org/10.3390/ijms21124311

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