Cargando…

Computer-Aided Ligand Discovery for Estrogen Receptor Alpha

Breast cancer (BCa) is one of the most predominantly diagnosed cancers in women. Notably, 70% of BCa diagnoses are Estrogen Receptor α positive (ERα+) making it a critical therapeutic target. With that, the two subtypes of ER, ERα and ERβ, have contrasting effects on BCa cells. While ERα promotes ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Bafna, Divya, Ban, Fuqiang, Rennie, Paul S., Singh, Kriti, Cherkasov, Artem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352601/
https://www.ncbi.nlm.nih.gov/pubmed/32545494
http://dx.doi.org/10.3390/ijms21124193