Cargando…
Hallmarks of Splicing Defects in Cancer: Clinical Applications in the Era of Personalized Medicine
Alternative splicing promotes proteome diversity by using limited number of genes, a key control point of gene expression. Splicing is carried out by large macromolecular machineries, called spliceosome, composed of small RNAs and proteins. Alternative splicing is regulated by splicing regulatory ci...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352608/ https://www.ncbi.nlm.nih.gov/pubmed/32481522 http://dx.doi.org/10.3390/cancers12061381 |