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Hallmarks of Splicing Defects in Cancer: Clinical Applications in the Era of Personalized Medicine

Alternative splicing promotes proteome diversity by using limited number of genes, a key control point of gene expression. Splicing is carried out by large macromolecular machineries, called spliceosome, composed of small RNAs and proteins. Alternative splicing is regulated by splicing regulatory ci...

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Detalles Bibliográficos
Autores principales: Rahman, Mohammad Alinoor, Nasrin, Farhana, Bhattacharjee, Sonali, Nandi, Saikat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352608/
https://www.ncbi.nlm.nih.gov/pubmed/32481522
http://dx.doi.org/10.3390/cancers12061381