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The Antihistamine Deptropine Induces Hepatoma Cell Death through Blocking Autophagosome-Lysosome Fusion

Some antihistamines have exhibited significant antitumor activity alone or in combination with other therapies in in vitro and clinical studies. However, the underlying mechanisms of how antihistamines inhibit hepatocellular carcinoma proliferation are still unknown. We first screened the antiprolif...

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Detalles Bibliográficos
Autores principales: Liang, Yu-Chih, Chang, Chi-Ching, Sheu, Ming-Thau, Lin, Shyr-Yi, Chung, Chia-Chen, Teng, Chang-Ting, Suk, Fat-Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352610/
https://www.ncbi.nlm.nih.gov/pubmed/32570749
http://dx.doi.org/10.3390/cancers12061610