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Clinical-Grade Peptide-Based Inhibition of CK2 Blocks Viability and Proliferation of T-ALL Cells and Counteracts IL-7 Stimulation and Stromal Support

Despite remarkable advances in the treatment of T-cell acute lymphoblastic leukemia (T-ALL), relapsed cases are still a major challenge. Moreover, even successful cases often face long-term treatment-associated toxicities. Targeted therapeutics may overcome these limitations. We have previously demo...

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Detalles Bibliográficos
Autores principales: Perera, Yasser, Melão, Alice, Ramón, Ailyn C., Vázquez, Dania, Ribeiro, Daniel, Perea, Silvio E., Barata, João T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352628/
https://www.ncbi.nlm.nih.gov/pubmed/32471246
http://dx.doi.org/10.3390/cancers12061377