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Clinical-Grade Peptide-Based Inhibition of CK2 Blocks Viability and Proliferation of T-ALL Cells and Counteracts IL-7 Stimulation and Stromal Support
Despite remarkable advances in the treatment of T-cell acute lymphoblastic leukemia (T-ALL), relapsed cases are still a major challenge. Moreover, even successful cases often face long-term treatment-associated toxicities. Targeted therapeutics may overcome these limitations. We have previously demo...
Autores principales: | Perera, Yasser, Melão, Alice, Ramón, Ailyn C., Vázquez, Dania, Ribeiro, Daniel, Perea, Silvio E., Barata, João T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352628/ https://www.ncbi.nlm.nih.gov/pubmed/32471246 http://dx.doi.org/10.3390/cancers12061377 |
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