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Hypoxanthine Phosphoribosyl Transferase 1 Is Upregulated, Predicts Clinical Outcome and Controls Gene Expression in Breast Cancer

Hypoxanthine phosphoribosyl transferase 1 (HPRT1) is traditionally believed to be a housekeeping gene; however, recent reports suggest that it is upregulated in several cancers and is associated with clinical outcomes. HPRT1 is located on chromosome X and encodes the HPRT enzyme, which functions in...

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Detalles Bibliográficos
Autores principales: J. Sedano, Melina, I. Ramos, Enrique, Choudhari, Ramesh, L. Harrison, Alana, Subramani, Ramadevi, Lakshmanaswamy, Rajkumar, Zilaie, Mina, Gadad, Shrikanth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352670/
https://www.ncbi.nlm.nih.gov/pubmed/32532008
http://dx.doi.org/10.3390/cancers12061522