A Synthetic Cell-Penetrating Heparin-Binding Peptide Derived from BMP4 with Anti-Inflammatory and Chondrogenic Functions for the Treatment of Arthritis

We report dual therapeutic effects of a synthetic heparin-binding peptide (HBP) corresponding to residues 15–24 of the heparin binding site in BMP4 in a collagen-induced rheumatic arthritis model (CIA) for the first time. The cell penetrating capacity of HBP led to improved cartilage recovery and an...

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Detalles Bibliográficos
Autores principales: Choi, Da Hyeon, Lee, Dongwoo, Jo, Beom Soo, Park, Kwang-Sook, Lee, Kyeong Eun, Choi, Ju Kwang, Park, Yoon Jeong, Lee, Jue-Yeon, Park, Yoon Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352680/
https://www.ncbi.nlm.nih.gov/pubmed/32549254
http://dx.doi.org/10.3390/ijms21124251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352680/
https://www.ncbi.nlm.nih.gov/pubmed/32549254
http://dx.doi.org/10.3390/ijms21124251

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