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Spectrum-Wide Exploration of Human Adenoviruses for Breast Cancer Therapy

Oncolytic adenoviruses (Ads) are promising tools for cancer therapeutics. However, most Ad-based therapies utilize Ad type 5 (Ad5), which displays unsatisfying efficiency in clinical trials, partly due to the low expression levels of its primary coxsackievirus and adenovirus receptor (CAR) on tumor...

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Detalles Bibliográficos
Autores principales: Mach, Nicolas, Gao, Jian, Schaffarczyk, Lukas, Janz, Sebastian, Ehrke-Schulz, Eric, Dittmar, Thomas, Ehrhardt, Anja, Zhang, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352696/
https://www.ncbi.nlm.nih.gov/pubmed/32486014
http://dx.doi.org/10.3390/cancers12061403