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Immunotherapies and Metastatic Cancers: Understanding Utility and Predictivity of Human Immune Cell Engrafted Mice in Preclinical Drug Development

Metastases cause high mortality in several cancers and immunotherapies are expected to be effective in the prevention and treatment of metastatic disease. However, only a minority of patients benefit from immunotherapies. This creates a need for novel therapies that are efficacious regardless of the...

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Detalles Bibliográficos
Autores principales: Kähkönen, Tiina E., Halleen, Jussi M., Bernoulli, Jenni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352707/
https://www.ncbi.nlm.nih.gov/pubmed/32570871
http://dx.doi.org/10.3390/cancers12061615