Roles of Histone Deacetylases and Inhibitors in Anticancer Therapy

Histones are the main structural proteins of eukaryotic chromatin. Histone acetylation/ deacetylation are the epigenetic mechanisms of the regulation of gene expression and are catalyzed by histone acetyltransferases (HAT) and histone deacetylases (HDAC). These epigenetic alterations of DNA structur...

Descripción completa

Detalles Bibliográficos
Autores principales: Verza, Flávia Alves, Das, Umashankar, Fachin, Ana Lúcia, Dimmock, Jonathan R., Marins, Mozart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352721/
https://www.ncbi.nlm.nih.gov/pubmed/32585896
http://dx.doi.org/10.3390/cancers12061664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352721/
https://www.ncbi.nlm.nih.gov/pubmed/32585896
http://dx.doi.org/10.3390/cancers12061664

Ejemplares similares