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Roles of Histone Deacetylases and Inhibitors in Anticancer Therapy

Histones are the main structural proteins of eukaryotic chromatin. Histone acetylation/ deacetylation are the epigenetic mechanisms of the regulation of gene expression and are catalyzed by histone acetyltransferases (HAT) and histone deacetylases (HDAC). These epigenetic alterations of DNA structur...

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Detalles Bibliográficos
Autores principales:	Verza, Flávia Alves, Das, Umashankar, Fachin, Ana Lúcia, Dimmock, Jonathan R., Marins, Mozart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352721/ https://www.ncbi.nlm.nih.gov/pubmed/32585896 http://dx.doi.org/10.3390/cancers12061664

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