SPOP Deregulation Improves the Radiation Response of Prostate Cancer Models by Impairing DNA Damage Repair

Speckle-type POZ (pox virus and zinc finger protein) protein (SPOP) is the most commonly mutated gene in prostate cancer (PCa). Recent evidence reports a role of SPOP in DNA damage response (DDR), indicating a possible impact of SPOP deregulation on PCa radiosensitivity. This study aimed to define t...

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Detalles Bibliográficos
Autores principales: El Bezawy, Rihan, Tripari, Martina, Percio, Stefano, Cicchetti, Alessandro, Tortoreto, Monica, Stucchi, Claudio, Tinelli, Stella, Zuco, Valentina, Doldi, Valentina, Gandellini, Paolo, Valdagni, Riccardo, Zaffaroni, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352729/
https://www.ncbi.nlm.nih.gov/pubmed/32512734
http://dx.doi.org/10.3390/cancers12061462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352729/
https://www.ncbi.nlm.nih.gov/pubmed/32512734
http://dx.doi.org/10.3390/cancers12061462

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