CAIX-Mediated Control of LIN28/let-7 Axis Contributes to Metabolic Adaptation of Breast Cancer Cells to Hypoxia

Solid tumors, including breast cancer, are characterized by the hypoxic microenvironment, extracellular acidosis, and chemoresistance. Hypoxia marker, carbonic anhydrase IX (CAIX), is a pH regulator providing a selective survival advantage to cancer cells through intracellular neutralization while f...

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Detalles Bibliográficos
Autores principales: Gibadulinova, Adriana, Bullova, Petra, Strnad, Hynek, Pohlodek, Kamil, Jurkovicova, Dana, Takacova, Martina, Pastorekova, Silvia, Svastova, Eliska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352761/
https://www.ncbi.nlm.nih.gov/pubmed/32560271
http://dx.doi.org/10.3390/ijms21124299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352761/
https://www.ncbi.nlm.nih.gov/pubmed/32560271
http://dx.doi.org/10.3390/ijms21124299

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