TRPV1 Antagonist DWP05195 Induces ER Stress-Dependent Apoptosis through the ROS-p38-CHOP Pathway in Human Ovarian Cancer Cells

In addition to their analgesic activity, transient receptor potential vanilloid 1 (TRPV1) agonists and antagonists demonstrate profound anti-cancer activities in various human cancers. In the present study, we investigated the anti-cancer activity of a novel TRPV1 antagonist, DWP05195, and evaluated...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Yue, Lee, Kyung-Tae, Lim, Myong Cheol, Choi, Jung-Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352786/
https://www.ncbi.nlm.nih.gov/pubmed/32604833
http://dx.doi.org/10.3390/cancers12061702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352786/
https://www.ncbi.nlm.nih.gov/pubmed/32604833
http://dx.doi.org/10.3390/cancers12061702

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