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Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression

Pseudokinases, comprising 10% of the human kinome, are emerging as regulators of canonical kinases and their functions are starting to be defined. We previously identified the pseudokinase Nuclear Receptor Binding Protein 2 (NRBP2) in a screen for genes regulated during neural differentiation. Durin...

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Detalles Bibliográficos
Autores principales: Xiong, Anqi, Roy, Ananya, Spyrou, Argyris, Weishaupt, Holger, Marinescu, Voichita D., Olofsson, Tommie, Hermanson, Ola, Swartling, Fredrik J., Forsberg-Nilsson, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352854/
https://www.ncbi.nlm.nih.gov/pubmed/32517178
http://dx.doi.org/10.3390/cancers12061483