Machine-Learned Association of Next-Generation Sequencing-Derived Variants in Thermosensitive Ion Channels Genes with Human Thermal Pain Sensitivity Phenotypes

Genetic association studies have shown their usefulness in assessing the role of ion channels in human thermal pain perception. We used machine learning to construct a complex phenotype from pain thresholds to thermal stimuli and associate it with the genetic information derived from the next-genera...

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Detalles Bibliográficos
Autores principales: Lötsch, Jörn, Kringel, Dario, Geisslinger, Gerd, Oertel, Bruno G., Resch, Eduard, Malkusch, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352872/
https://www.ncbi.nlm.nih.gov/pubmed/32575443
http://dx.doi.org/10.3390/ijms21124367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352872/
https://www.ncbi.nlm.nih.gov/pubmed/32575443
http://dx.doi.org/10.3390/ijms21124367

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