Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation

Colorectal cancer represents one of the most prevalent malignancies globally, with an estimated 140,000 new cases in the United States alone in 2019. Despite advancements in interventions, drug resistance occurs in virtually all patients diagnosed with late stages of colon cancer. Amplified epiderma...

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Detalles Bibliográficos
Autores principales: Yadav, Vijesh Kumar, Huang, Yan-Jiun, George, Thomashire Anita, Wei, Po-Li, Sumitra, Maryam rachmawati, Ho, Ching-Liang, Chang, Tzu-Hao, Wu, Alexander T. H., Huang, Hsu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352915/
https://www.ncbi.nlm.nih.gov/pubmed/32560222
http://dx.doi.org/10.3390/cancers12061590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352915/
https://www.ncbi.nlm.nih.gov/pubmed/32560222
http://dx.doi.org/10.3390/cancers12061590

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