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Metabolic Landscape of a Genetically Engineered Mouse Model of IDH1 Mutant Glioma

Understanding the metabolic reprogramming of aggressive brain tumors has potential applications for therapeutics as well as imaging biomarkers. However, little is known about the nutrient requirements of isocitrate dehydrogenase 1 (IDH1) mutant gliomas. The IDH1 mutation involves the acquisition of...

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Detalles Bibliográficos
Autores principales: Ruiz-Rodado, Victor, Seki, Tomohiro, Dowdy, Tyrone, Lita, Adrian, Zhang, Meili, Han, Sue, Yang, Chunzhang, Cherukuri, Murali K., Gilbert, Mark R., Larion, Mioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352932/
https://www.ncbi.nlm.nih.gov/pubmed/32575619
http://dx.doi.org/10.3390/cancers12061633