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Peptides Derived from (RRWQWRMKKLG)(2-)K-Ahx Induce Selective Cellular Death in Breast Cancer Cell Lines through Apoptotic Pathway

The effect on the cytotoxicity against breast cancer cell lines of the substitution of (26)Met residue in the sequence of the Bovine Lactoferricin-derived dimeric peptide LfcinB (20-30)(2): ((20)RRWQWRMKKLG(30))(2)-K-Ahx with amino acids of different polarity was evaluated. The process of the synthe...

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Detalles Bibliográficos
Autores principales: Insuasty-Cepeda, Diego Sebastián, Barragán-Cárdenas, Andrea Carolina, Ochoa-Zarzosa, Alejandra, López-Meza, Joel E., Fierro-Medina, Ricardo, García-Castañeda, Javier Eduardo, Rivera-Monroy, Zuly Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352952/
https://www.ncbi.nlm.nih.gov/pubmed/32604743
http://dx.doi.org/10.3390/ijms21124550